30-0-6 is my favorite all around caliber...i can use lighter 125 gr loads for varmints, wolves and coyotes and the like, the heavier 180-220 grainers for moose and bear and caribou, and ive even used it for grizzlies without too much fear...the 165 grain rounds are perfect for long range shots on mountain goat and dall sheep...though i prefer overall the 180s. i have successfully hunted moose, caribou, elk, white/blacktail, goat, sheep, grizzly and black bear with few setbacks....youll learn to love it or hate it. good choice Monk